Exploring chromosomal structural heterogeneity across multiple cell lines
نویسندگان
چکیده
منابع مشابه
Chromosomal heterogeneity in the RAG and MSWBS mouse tumor cell lines.
By means of a Q-banding technique, virtually every chromosome in two heteroploid mouse cell lines, RAG and MSWBS, has been identified. The origin of 60 to 80% of the chromosomes has been established; the remaining chromo somes can be identified as markers characteristic of the cell line. The extent of chromosome heterogeneity has been ex amined and compared in these two mouse tumor cell lines. ...
متن کاملChromosomal variation in lymphoblastoid cell lines.
Tens of thousands of lymphoblastoid cell lines (LCLs) have been established by the research community, providing nearly unlimited source material from samples of interest. LCLs are used to address questions in population genomics, mechanisms of disease, and pharmacogenomics. Thus, it is of fundamental importance to define the extent of chromosomal variation in LCLs. We measured variation in gen...
متن کاملExploring super-resolution implementations across multiple platforms
The performance of many applications, such as video streaming, webcam conferencing, and aerial surveillance, all greatly depend on video quality. A major issue with higher quality video is that either more data bandwidth or storage resources must be dedicated for transferring or storing the video. However, if the low-resolution video is transferred or stored in order to conserve data bandwidth ...
متن کاملHeterogeneity of transcription factor binding specificity models within and across cell lines.
Complex gene expression patterns are mediated by the binding of transcription factors (TFs) to specific genomic loci. The in vivo occupancy of a TF is, in large part, determined by the TF's DNA binding interaction partners, motivating genomic context-based models of TF occupancy. However, approaches thus far have assumed a uniform TF binding model to explain genome-wide cell-type-specific bindi...
متن کاملGenomic Heterogeneity and Structural Variation in Soybean Near Isogenic Lines
Near isogenic lines (NILs) are a critical genetic resource for the soybean research community. The ability to identify and characterize the genes driving the phenotypic differences between NILs is limited by the degree to which differential genetic introgressions can be resolved. Furthermore, the genetic heterogeneity extant among NIL sub-lines is an unaddressed research topic that might have i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: eLife
سال: 2020
ISSN: 2050-084X
DOI: 10.7554/elife.60312